Acute poststreptococcal glomerulonephritis and acute rheumatic fever: An uncommon coincidence

IgA-dominant acute poststreptococcal glomerulonephritis with concomitant rheumatic fever successfully treated with steroids: a case report

There are only a few reports of the co-occurrence of acute poststreptococcal glomerulonephritis (APGN) and acute rheumatic fever. We report an unusual case of a 3-year-old boy with nephrotic syndrome and acute renal failure with the transitional need for peritoneal dialysis, biopsy-proven atypical IgA-dominant APGN, and concomitant acute rheumatic fever, successfully treated by steroids. Aggres...

Acute poststreptococcal glomerulonephritis and acute rheumatic fever in the same patient: a case report and review of the literature.

Atypical Clinical Manifestations of Acute Poststreptococcal Glomerulonephritis

Acute poststreptococcal glomerulonephritis (APSGN) is one of the most common and important renal diseases resulting from a prior infection with group A β-hemolytic streptococcus (GAS) (Ash and Ingulli, 2008). Typical clinical features of the disease include an acute onset with gross hematuria, edema, hypertension and moderate proteinuria (acute nephritic syndrome) 1 to 2 weeks after an antecede...

Acute poststreptococcal glomerulonephritis: immune deposit disease.

The possible role of immunologic mechanisms in acute poststreptococcal glomerulonephritis was suggested in 1908 by Schick (2), who compared the delay in appearance of serum sickness after injection of heterologous serum to the latent period between scarlet fever and onset of acute glomerulonephritis. Evidence in support of this concept is the depression of serum complement during the early stag...

Acute rheumatic fever.

Acute rheumatic fever is an inflammatory response to group A streptococcal infectionwhich typically occurs two to three weeks after a throat infection.Worldwide, approximately 500 000 new cases of acute rheumatic fever occur annually, and at least 15 million people have chronic rheumatic heart disease. 2 Acute rheumatic fever is characterised by a clinical syndrome, and the most common manifest...